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California researchers develop new strategy to get novel antibiotics for bacterial infections Researchers at the University of California, Santa Cruz, have developed a new technique for locating novel antibiotic compounds, using a diagnostic panel of bacterial strains for screening chemical substance extracts from natural resources. Public health officials warn of a looming antibiotic crisis due to the steady increase in antibiotic level of resistance and a dramatic decline in the advancement of new antibiotics rx pills . Most currently available antibiotics are derived from natural compounds made by microorganisms such as fungi and bacteria. New antibiotics produced by drug companies are synthetically tailored variations of existing classes of antibiotics often.