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Predicated on proof from these studies, benzodiazepines were connected with no improvement in or worsening of general intensity, psychotherapy outcomes, aggression, melancholy, and substance make use of in PTSD individuals. Twelve research provided data adequate for a meta-analysis. The outcomes suggested that benzodiazepines had been connected with no improvement in PTSD-related outcomes, and that using benzodiazepines in patients with latest trauma in fact increased PTSD risk. Those studies providing enough data suggest that the chance of developing PTSD is definitely two to five moments higher in groups getting benzodiazepines than in charge groups, Dr. Coauthors and Guina write. It could be because nervousness in PTSD develops in different ways than in other panic disorders.